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Polymer nanomedicine and biological blood vessels

Polymer nano drugs and vascular biological interface research and application is a hot area involving multidisciplinary crossover, the main purpose is to use polymer nanomaterials as drug carrier, by regulating its interaction with vascular endothelial cells, blood components, tumor cells, realize the targeted delivery, control release and enhance the treatment effect.

Realize tumor vascular embolization treatment using polymer nanomedicine. The polymer nanomedicines are nanorobots made of self-assembly of DNA molecules and can carry an enzyme capable of inducing blood coagulation, namely thrombin. When the nanorobot reaches the tumor blood vessel, it is recognized and engulfed by the receptors on the surface of the tumor cells, and then releases thrombin inside the cell, resulting in the blood in the tumor blood vessel, thus cutting off the nutrient supply of the tumor and realizing the ischemia and necrosis of the tumor.

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