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Nanozyme:IrOx-GOD

Nanozyme:IrOx-GOD

【Numbering】BKMA100018 【CAS】cas
【Item No.】BKMA100018-2 【specification】
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Name: IrOx-GOD
Composition of: IrOx, GOD
Particle size: 20~50 nm
Application: To regulate the glucose or reactive oxygen species metabolism in tumors
Storage conditions: -4℃, -20℃
Other instructions: You will have a shelf life of half a year in the sealed state

[Main advantages] 1. Glucaric acid can produce O2 and OH through the release of oxidase and peroxidase-like activities of IrOx; 2, IrOx can also continuously consume glutathione (GSH) by alternating the self-cyclic valence of IrIV and IrIII, Breaking down the tumor's antioxidant defense system; 3, simply introducing the prepared nanoenzymes into the tumor system may lead to the "butterfly effect" of oxygen stress and starvation therapy, Adaptive evolution can be broken by maximum perturbation to the deterministic box boundary conditions of the system microenvironment, Disdestroy scrambled tumors without enhancing ROS scavenging of enzymes and antioxidant molecules, Thus outperforming conventional ROS and gsh-targeted therapies.

Title:Specific “Unlocking” of a Nanozyme-Based Butterfly Effect To Break the Evolutionary Fitness of Chaotic Tumors
Article link:https://doi.org/10.1002/anie.201916142

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    類過氧化物酶(POD)

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